Trending Skills
The hottest skills gaining momentum in the community right now.
tooluniverse-immune-repertoire-analysis
by mims-harvard
Comprehensive immune repertoire analysis for T-cell and B-cell receptor sequencing data. Analyze TCR/BCR repertoires to assess clonality, diversity, V(D)J gene usage, CDR3 characteristics, convergence, and predict epitope specificity. Integrate with single-cell data for clonotype-phenotype associations. Use for adaptive immune response profiling, cancer immunotherapy research, vaccine response assessment, autoimmune disease studies, or repertoire diversity analysis in immunology research.
tooluniverse-gwas-study-explorer
by mims-harvard
Compare GWAS studies, perform meta-analyses, and assess replication across cohorts. Integrates NHGRI-EBI GWAS Catalog and Open Targets Genetics to compare study designs, effect sizes, ancestry diversity, and heterogeneity statistics. Use when comparing GWAS studies for a trait, performing meta-analysis of genetic loci, assessing replication across cohorts, or exploring the genetic architecture of complex diseases.
tooluniverse-epigenomics
by mims-harvard
Production-ready genomics and epigenomics data processing for BixBench questions. Handles methylation array analysis (CpG filtering, differential methylation, age-related CpG detection, chromosome-level density), ChIP-seq peak analysis (peak calling, motif enrichment, coverage stats), ATAC-seq chromatin accessibility, multi-omics integration (expression + methylation correlation), and genome-wide statistics. Pure Python computation (pandas, scipy, numpy, pysam, statsmodels) plus ToolUniverse annotation tools (Ensembl, ENCODE, SCREEN, JASPAR, ReMap, RegulomeDB, ChIPAtlas). Supports BED, BigWig, methylation beta-value matrices, Illumina manifest files, and multi-sample clinical data. Use when processing methylation data, ChIP-seq peaks, ATAC-seq signals, or answering questions about CpG sites, differential methylation, chromatin accessibility, histone marks, or epigenomic statistics.
devtu-create-tool
by mims-harvard
Create new scientific tools for ToolUniverse framework with proper structure, validation, and testing. Use when users need to add tools to ToolUniverse, implement new API integrations, create tool wrappers for scientific databases/services, expand ToolUniverse capabilities, or follow ToolUniverse contribution guidelines. Supports creating tool classes, JSON configurations, validation, error handling, and test examples.
create-cowork-plugin
by anthropics
Guide users through creating a new plugin from scratch in a cowork session. Use when users want to create a plugin, build a plugin, make a new plugin, develop a plugin, scaffold a plugin, start a plugin from scratch, or design a plugin. This skill requires Cowork mode with access to the outputs directory for delivering the final .plugin file.
redesign-existing-projects
by Leonxlnx
Upgrades existing websites and apps to premium quality. Audits current design, identifies generic AI patterns, and applies high-end design standards without breaking functionality. Works with any CSS framework or vanilla CSS.
minimalist-ui
by Leonxlnx
Clean editorial-style interfaces. Warm monochrome palette, typographic contrast, flat bento grids, muted pastels. No gradients, no heavy shadows.
brandkit
by Leonxlnx
Premium brand-kit image generation skill for creating high-end brand-guidelines boards, logo systems, identity decks, and visual-world presentations. Trained for minimalist, cinematic, editorial, dark-tech, luxury, cultural, security, gaming, developer-tool, and consumer-app brand systems. Optimized for intentional logo concepting, refined composition, sparse typography, strong symbolic meaning, premium mockups, art-directed imagery, and flexible grid layouts.
design-taste-frontend
by Leonxlnx
Senior UI/UX Engineer. Architect digital interfaces overriding default LLM biases. Enforces metric-based rules, strict component architecture, CSS hardware acceleration, and balanced design engineering.
redesign-existing-projects
by Leonxlnx
Upgrades existing websites and apps to premium quality. Audits current design, identifies generic AI patterns, and applies high-end design standards without breaking functionality. Works with any CSS framework or vanilla CSS.
full-output-enforcement
by Leonxlnx
Overrides default LLM truncation behavior. Enforces complete code generation, bans placeholder patterns, and handles token-limit splits cleanly. Apply to any task requiring exhaustive, unabridged output.
design-taste-frontend
by Leonxlnx
Senior UI/UX Engineer. Architect digital interfaces overriding default LLM biases. Enforces metric-based rules, strict component architecture, CSS hardware acceleration, and balanced design engineering.
quien
by retlehs
"Use the quien CLI for domain and IP lookups: WHOIS/RDAP, DNS, mail authentication, TLS certificates, HTTP headers, SEO analysis, and tech stack detection. Activate when the user asks about a domain's owner, registrar, expiry, DNS records, mail config (SPF, DMARC, DKIM, BIMI), SSL certificate, HTTP headers, SEO, Core Web Vitals, tech stack, CMS, hosting, or IP address info (ASN, network, abuse contact)."
high-end-visual-design
by Leonxlnx
Teaches the AI to design like a high-end agency. Defines the exact fonts, spacing, shadows, card structures, and animations that make a website feel expensive. Blocks all the common defaults that make AI designs look cheap or generic.
imagegen-frontend-web
by Leonxlnx
Elite frontend image-direction skill for generating premium, artistic, implementation-friendly website design references. Uses combinatorial variation to avoid repetitive AI aesthetics, enforces cinematic hero minimalism, strong hierarchy, generous spacing, image-led composition, and anti-slop visual discipline. Optimized for hero sections, landing pages, and multi-section site comps that developers or coding models can accurately recreate.
imagegen-frontend-mobile
by Leonxlnx
Elite mobile app image-generation skill for creating premium, app-native screen concepts and flows. Designed for iOS, Android, and cross-platform mobile products. Prioritizes clean hierarchy, comfortably readable text, strong multi-screen consistency, controlled color palettes, non-generic creative direction, textured surfaces, image-led composition, tasteful custom iconography, and clean phone mockup framing. By default, screens should be shown inside a subtle premium iPhone or similar phone mockup with a visible frame, while the main focus stays on the app content itself. This skill generates images only. It does not write code.
image-to-code
by Leonxlnx
Elite website image-to-code skill for Codex. For visually important web tasks, it must first generate the design image(s) itself, deeply analyze them, then implement the website to match them as closely as possible. In Codex, it must prefer large, readable, section-specific images instead of tiny compressed boards, generate fresh standalone images for sections or detail views instead of cropping old ones, avoid lazy under-generation, avoid cards-inside-cards-inside-cards UI, and keep the hero clean, spacious, readable, and visible on a small laptop.
industrial-brutalist-ui
by Leonxlnx
Raw mechanical interfaces fusing Swiss typographic print with military terminal aesthetics. Rigid grids, extreme type scale contrast, utilitarian color, analog degradation effects. For data-heavy dashboards, portfolios, or editorial sites that need to feel like declassified blueprints.
high-end-visual-design
by Leonxlnx
Teaches the AI to design like a high-end agency. Defines the exact fonts, spacing, shadows, card structures, and animations that make a website feel expensive. Blocks all the common defaults that make AI designs look cheap or generic.
full-output-enforcement
by Leonxlnx
Overrides default LLM truncation behavior. Enforces complete code generation, bans placeholder patterns, and handles token-limit splits cleanly. Apply to any task requiring exhaustive, unabridged output.
design-taste-frontend-v1
by Leonxlnx
The original v1 taste-skill, preserved for projects depending on its exact behavior. The current default is design-taste-frontend (v2 experimental), which is a substantial rewrite. Use this v1 install name only if you need exact backward compatibility.
stitch-design-taste
by Leonxlnx
Semantic Design System Skill for Google Stitch. Generates agent-friendly DESIGN.md files that enforce premium, anti-generic UI standards — strict typography, calibrated color, asymmetric layouts, perpetual micro-motion, and hardware-accelerated performance.
dbs-benchmark
by dontbesilent2025
dontbesilent 对标分析。用五重过滤法帮你找到值得模仿的对标,排除一切关于「我」的噪音。 触发方式:/dbs-benchmark、/对标、「帮我找对标」「我该模仿谁」 Benchmark analysis using dontbesilent's five-filter method. Trigger: /dbs-benchmark, "find me a benchmark", "who should I copy"
analyzing-typosquatting-domains-with-dnstwist
by mukul975
Detect typosquatting, homograph phishing, and brand impersonation domains using dnstwist to generate domain permutations and identify registered lookalike domains targeting your organization.