Processing
Data transformation and parsing
equity-scorer
by ClawBio
Compute HEIM diversity and equity metrics from VCF or ancestry data. Generates heterozygosity, FST, PCA plots, and a composite HEIM Equity Score with markdown reports.
python-patterns
by affaan-m
Pythonic idioms, PEP 8 standards, type hints, and best practices for building robust, efficient, and maintainable Python applications.
weather-fetcher
by shanraisshan
Instructions for fetching current weather temperature data for Karachi, Pakistan from wttr.in API
tooluniverse-multi-omics-integration
by mims-harvard
Integrate and analyze multiple omics datasets (transcriptomics, proteomics, epigenomics, genomics, metabolomics) for systems biology and precision medicine. Performs cross-omics correlation, multi-omics clustering (MOFA+, NMF), pathway-level integration, and sample matching. Coordinates ToolUniverse skills for expression data (RNA-seq), epigenomics (methylation, ChIP-seq), variants (SNVs, CNVs), protein interactions, and pathway enrichment. Use when analyzing multi-omics datasets, performing integrative analysis, discovering multi-omics biomarkers, studying disease mechanisms across molecular layers, or conducting systems biology research that requires coordinated analysis of transcriptome, genome, epigenome, proteome, and metabolome data.
tooluniverse-cancer-variant-interpretation
by mims-harvard
Provide comprehensive clinical interpretation of somatic mutations in cancer. Given a gene symbol + variant (e.g., EGFR L858R, BRAF V600E) and optional cancer type, performs multi-database analysis covering clinical evidence (CIViC), mutation prevalence (cBioPortal), therapeutic associations (OpenTargets, ChEMBL, FDA), resistance mechanisms, clinical trials, prognostic impact, and pathway context. Generates an evidence-graded markdown report with actionable recommendations for precision oncology. Use when oncologists, molecular tumor boards, or researchers ask about treatment options for specific cancer mutations, resistance mechanisms, or clinical trial matching.
create-cli
by steipete
Design command-line interface parameters and UX: arguments, flags, subcommands, help text, output formats, error messages, exit codes, prompts, config/env precedence, and safe/dry-run behavior. Use when you’re designing a CLI spec (before implementation) or refactoring an existing CLI’s surface area for consistency, composability, and discoverability.
setup
by jau123
Configure MeiGen plugin provider and API keys. Use this when the user runs /meigen:setup, asks to "configure meigen", "set up image generation", "add API key", or needs help configuring the plugin.
Plugin Structure
by Galaxy-Dawn
This skill should be used when the user asks to "create a plugin", "scaffold a plugin", "understand plugin structure", "organize plugin components", "set up plugin.json", "use ${CLAUDE_PLUGIN_ROOT}", "add commands/agents/skills/hooks", "configure auto-discovery", or needs guidance on plugin directory layout, manifest configuration, component organization, file naming conventions, or Claude Code plugin architecture best practices.
tool-creator
by xuiltul
AnimaWorks用のPythonツールモジュールを正しいインターフェースで作成するメタスキル。 個人ツール（animas/{name}/tools/）・共有ツール（common_tools/）の作成手順、 ExternalToolDispatcher連携、use_tool経由の呼び出し、get_credentialによるAPIキー管理、 permissions.md許可設定、EXECUTION_PROFILEによる長時間実行対応を提供。 Web API連携・外部サービス統合のカスタムツール開発時に使用。 「ツールを作成」「ツール化」「新しいツール」「カスタムツール」「Python ツール」
MCP Integration
by Galaxy-Dawn
This skill should be used when the user asks to "add MCP server", "integrate MCP", "configure MCP in plugin", "use .mcp.json", "set up Model Context Protocol", "connect external service", mentions "${CLAUDE_PLUGIN_ROOT} with MCP", or discusses MCP server types (SSE, stdio, HTTP, WebSocket). Provides comprehensive guidance for integrating Model Context Protocol servers into Claude Code plugins for external tool and service integration.
market-research
by affaan-m
Conduct market research, competitive analysis, investor due diligence, and industry intelligence with source attribution and decision-oriented summaries. Use when the user wants market sizing, competitor comparisons, fund research, technology scans, or research that informs business decisions.
ai-native-cli
by sickn33
"Design spec with 98 rules for building CLI tools that AI agents can safely use. Covers structured JSON output, error handling, input contracts, safety guardrails, exit codes, and agent self-description."
scrna-orchestrator
by ClawBio
Automate single-cell RNA-seq analysis with Scanpy or Seurat. QC, normalisation, clustering, DE analysis, and visualisation.
angular-ui-patterns
by sickn33
Modern Angular UI patterns for loading states, error handling, and data display. Use when building UI components, handling async data, or managing component states.
fixing-metadata
by ibelick
Audit and fix HTML metadata including page titles, meta descriptions, canonical URLs, Open Graph tags, Twitter cards, favicons, JSON-LD structured data, and robots directives. Use when adding SEO metadata, fixing social share previews, reviewing Open Graph tags, setting up canonical URLs, or shipping new pages that need correct meta tags.
agent-orchestrator
by sickn33
Meta-skill que orquestra todos os agentes do ecossistema. Scan automatico de skills, match por capacidades, coordenacao de workflows multi-skill e registry management.
github-issue-solve
by holon-run
"Solve GitHub issues by implementing features or fixes and creating pull requests. Use when: (1) Implementing features described in issues, (2) Fixing bugs reported in issues, (3) Creating PRs from issue requirements."
douyin-batch-download
by cat-xierluo
抖音视频批量下载工具 - 基于 F2 框架实现高效、增量的视频下载功能。支持单个/批量博主下载，自动 Cookie 管理，差量更新机制。本技能应在用户需要批量下载特定博主视频、服务器部署自动化下载、或定期更新视频库时使用。
prompt-engineering
by rohitg00
Prompt engineering patterns including structured prompts, chain-of-thought, few-shot learning, and system prompt design
authentication-patterns
by rohitg00
Authentication and authorization patterns including OAuth2, JWT, RBAC, session management, and PKCE flows
github-auto-star
by cat-xierluo
"从内容（文章、截图、文字）中自动提取 GitHub 仓库并 star。使用场景：(1) 用户要求分析内容并 star 相关 GitHub 项目，(2) 处理提到工具或库的文章/博客，(3) 分析包含技术引用的截图，(4) 设置定时任务自动发现并 star 仓库。"
ads-youtube
by AgriciDaniel
YouTube Ads specific analysis covering campaign types, creative quality, audience targeting, and measurement. Evaluates video ad performance across skippable, non-skippable, bumper, Shorts, and Demand Gen formats. Use when user says "YouTube Ads", "video ads", "pre-roll", "bumper ads", "YouTube campaign", or "Shorts ads".
ads-creative
by AgriciDaniel
Cross-platform creative quality audit covering ad copy, video, image, and format diversity across all platforms. Detects creative fatigue, evaluates platform-native compliance, and provides production priorities. Use when user says "creative audit", "ad creative", "creative fatigue", "ad copy", "ad design", or "creative review".
tooluniverse-network-pharmacology
by mims-harvard
Construct and analyze compound-target-disease networks for drug repurposing, polypharmacology discovery, and systems pharmacology. Builds multi-layer networks from ChEMBL, OpenTargets, STRING, DrugBank, Reactome, FAERS, and 60+ other ToolUniverse tools. Calculates Network Pharmacology Scores (0-100), identifies repurposing candidates, predicts mechanisms, and analyzes polypharmacology. Use when users ask about drug repurposing via network analysis, multi-target drug effects, compound-target-disease networks, systems pharmacology, or polypharmacology.