数据处理
数据转换、清洗与 ETL
integrate-whatsapp
gokapso
"Connect WhatsApp to your product with Kapso: onboard customers with setup links, detect connections, receive events via webhooks, and send messages/templates/media. Also manage WhatsApp Flows (create/update/publish, data endpoints, encryption). Use when integrating WhatsApp end-to-end."
generic-react-feature-developer
travisjneuman
Guide feature development for React applications with architecture focus. Covers Zustand/Redux patterns, IndexedDB usage, component systems, lazy loading strategies, and seamless integration. Use when adding new features, refactoring existing code, or planning major changes.
customer-persona-builder
travisjneuman
Data-driven customer persona development combining market research, user behavior analysis, and segmentation frameworks. Use when creating buyer personas, ideal customer profiles (ICPs), or user archetypes.
case-interview-practice
travisjneuman
Interactive consulting case interview practice with structured frameworks, feedback mechanisms, and progressive difficulty. Use when preparing for management consulting interviews, case competitions, or business problem-solving exercises.
sqlite-adonet
dotnet
'Implementation details for the Microsoft.Data.Sqlite ADO.NET provider. Use when changing files under src/Microsoft.Data.Sqlite.Core/.'
cosmos-provider
dotnet
'Implementation details for the EF Core Azure Cosmos DB provider. Use when changing Cosmos-specific code.'
tooluniverse-gwas-snp-interpretation
mims-harvard
Interpret genetic variants (SNPs) from GWAS studies by aggregating evidence from multiple databases (GWAS Catalog, Open Targets Genetics, ClinVar). Retrieves variant annotations, GWAS trait associations, fine-mapping evidence, locus-to-gene predictions, and clinical significance. Use when asked to interpret a SNP by rsID, find disease associations for a variant, assess clinical significance, or answer questions like "What diseases is rs429358 associated with?" or "Interpret rs7903146".
tooluniverse-multi-omics-integration
mims-harvard
Integrate and analyze multiple omics datasets (transcriptomics, proteomics, epigenomics, genomics, metabolomics) for systems biology and precision medicine. Performs cross-omics correlation, multi-omics clustering (MOFA+, NMF), pathway-level integration, and sample matching. Coordinates ToolUniverse skills for expression data (RNA-seq), epigenomics (methylation, ChIP-seq), variants (SNVs, CNVs), protein interactions, and pathway enrichment. Use when analyzing multi-omics datasets, performing integrative analysis, discovering multi-omics biomarkers, studying disease mechanisms across molecular layers, or conducting systems biology research that requires coordinated analysis of transcriptome, genome, epigenome, proteome, and metabolome data.
tooluniverse-binder-discovery
mims-harvard
Discover novel small molecule binders for protein targets using structure-based and ligand-based approaches. Creates actionable reports with candidate compounds, ADMET profiles, and synthesis feasibility. Use when users ask to find small molecules for a target, identify novel binders, perform virtual screening, or need hit-to-lead compound identification.
tooluniverse-network-pharmacology
mims-harvard
Construct and analyze compound-target-disease networks for drug repurposing, polypharmacology discovery, and systems pharmacology. Builds multi-layer networks from ChEMBL, OpenTargets, STRING, DrugBank, Reactome, FAERS, and 60+ other ToolUniverse tools. Calculates Network Pharmacology Scores (0-100), identifies repurposing candidates, predicts mechanisms, and analyzes polypharmacology. Use when users ask about drug repurposing via network analysis, multi-target drug effects, compound-target-disease networks, systems pharmacology, or polypharmacology.
devtu-optimize-skills
mims-harvard
Optimize ToolUniverse skills for better report quality, evidence handling, and user experience. Apply patterns like tool verification, foundation data layers, disambiguation-first, evidence grading, quantified completeness, and report-only output. Use when reviewing skills, improving existing skills, or creating new ToolUniverse research skills.
tooluniverse-precision-medicine-stratification
mims-harvard
Comprehensive patient stratification for precision medicine by integrating genomic, clinical, and therapeutic data. Given a disease/condition, genomic data (germline variants, somatic mutations, expression), and optional clinical parameters, performs multi-phase analysis across 9 phases covering disease disambiguation, genetic risk assessment, disease-specific molecular stratification, pharmacogenomic profiling, comorbidity/DDI risk, pathway analysis, clinical evidence and guideline mapping, clinical trial matching, and integrated outcome prediction. Generates a quantitative Precision Medicine Risk Score (0-100) with risk tier assignment (Low/Intermediate/High/Very High), treatment algorithm (1st/2nd/3rd line), pharmacogenomic guidance, clinical trial matches, and monitoring plan. Use when clinicians ask about patient risk stratification, treatment selection, prognosis prediction, or personalized therapeutic strategy across cancer, metabolic, cardiovascular, neurological, or rare diseases.
tooluniverse-image-analysis
mims-harvard
Production-ready microscopy image analysis and quantitative imaging data skill for colony morphometry, cell counting, fluorescence quantification, and statistical analysis of imaging-derived measurements. Processes ImageJ/CellProfiler output (area, circularity, intensity, cell counts), performs Dunnett's test, Cohen's d effect size, power analysis, Shapiro-Wilk normality tests, two-way ANOVA, polynomial regression, natural spline regression with confidence intervals, and comparative morphometry. Supports CSV/TSV measurement tables, multi-channel fluorescence data, colony swarming assays, and neuron counting datasets. Use when analyzing microscopy measurement data, colony area/circularity, cell count statistics, swarming assays, co-culture ratio optimization, or answering questions about imaging-derived quantitative data.
tooluniverse-chemical-compound-retrieval
mims-harvard
Retrieves chemical compound information from PubChem and ChEMBL with disambiguation, cross-referencing, and quality assessment. Creates comprehensive compound profiles with identifiers, properties, bioactivity, and drug information. Use when users need chemical data, drug information, or mention PubChem CID, ChEMBL ID, SMILES, InChI, or compound names.
tooluniverse-multiomic-disease-characterization
mims-harvard
Comprehensive multi-omics disease characterization integrating genomics, transcriptomics, proteomics, pathway, and therapeutic layers for systems-level understanding. Produces a detailed multi-omics report with quantitative confidence scoring (0-100), cross-layer gene concordance analysis, biomarker candidates, therapeutic opportunities, and mechanistic hypotheses. Uses 80+ ToolUniverse tools across 8 analysis layers. Use when users ask about disease mechanisms, multi-omics analysis, systems biology of disease, biomarker discovery, or therapeutic target identification from a disease perspective.
tooluniverse-clinical-guidelines
mims-harvard
Search and retrieve clinical practice guidelines across 12+ authoritative sources including NICE, WHO, ADA, AHA/ACC, NCCN, SIGN, CPIC, CMA, CTFPHC, GIN, MAGICapp, PubMed, EuropePMC, TRIP, and OpenAlex. Covers disease management, cardiology, oncology, diabetes, pharmacogenomics, and more. Use when users ask about clinical guidelines, treatment recommendations, standard of care, evidence-based medicine, or drug-gene dosing recommendations.
setup-tooluniverse
mims-harvard
Install and configure ToolUniverse with MCP integration for any AI coding client (Cursor, Claude Desktop, Windsurf, VS Code, Codex, Gemini CLI, Trae, Cline, Antigravity, OpenCode, etc.). Covers uv/uvx setup, MCP configuration, API key walkthrough, skill installation, and upgrading. Use when setting up ToolUniverse, configuring MCP servers, troubleshooting installation issues, upgrading versions, or when user mentions installing ToolUniverse or setting up scientific tools.
tooluniverse-metabolomics-analysis
mims-harvard
Analyze metabolomics data including metabolite identification, quantification, pathway analysis, and metabolic flux. Processes LC-MS, GC-MS, NMR data from targeted and untargeted experiments. Performs normalization, statistical analysis, pathway enrichment, metabolite-enzyme integration, and biomarker discovery. Use when analyzing metabolomics datasets, identifying differential metabolites, studying metabolic pathways, integrating with transcriptomics/proteomics, discovering metabolic biomarkers, performing flux balance analysis, or characterizing metabolic phenotypes in disease, drug response, or physiological conditions.
tooluniverse-immunotherapy-response-prediction
mims-harvard
Predict patient response to immune checkpoint inhibitors (ICIs) using multi-biomarker integration. Given a cancer type, somatic mutations, and optional biomarkers (TMB, PD-L1, MSI status), performs systematic analysis across 11 phases covering TMB classification, neoantigen burden estimation, MSI/MMR assessment, PD-L1 evaluation, immune microenvironment profiling, mutation-based resistance/sensitivity prediction, clinical evidence retrieval, and multi-biomarker score integration. Generates a quantitative ICI Response Score (0-100), response likelihood tier, specific ICI drug recommendations with evidence, resistance risk factors, and a monitoring plan. Use when oncologists ask about immunotherapy eligibility, checkpoint inhibitor selection, or biomarker-guided ICI treatment decisions.
tooluniverse-cancer-variant-interpretation
mims-harvard
Provide comprehensive clinical interpretation of somatic mutations in cancer. Given a gene symbol + variant (e.g., EGFR L858R, BRAF V600E) and optional cancer type, performs multi-database analysis covering clinical evidence (CIViC), mutation prevalence (cBioPortal), therapeutic associations (OpenTargets, ChEMBL, FDA), resistance mechanisms, clinical trials, prognostic impact, and pathway context. Generates an evidence-graded markdown report with actionable recommendations for precision oncology. Use when oncologists, molecular tumor boards, or researchers ask about treatment options for specific cancer mutations, resistance mechanisms, or clinical trial matching.
higress-wasm-go-plugin
alibaba
Develop Higress WASM plugins using Go 1.24+. Use when creating, modifying, or debugging Higress gateway plugins for HTTP request/response processing, external service calls, Redis integration, or custom gateway logic.
apify-ecommerce
apify
Scrape e-commerce data for pricing intelligence, customer reviews, and seller discovery across Amazon, Walmart, eBay, IKEA, and 50+ marketplaces. Use when user asks to monitor prices, track competitors, analyze reviews, research products, or find sellers.
seo-coach
akseolabs-seo
Beginner-first SEO coaching for people who want to learn by doing one safe, verifiable step at a time. Use for SEO 陪跑、學 SEO、逐步檢查網站、看懂 Search Console／GA4、零付費工具的手動無痕 SERP、關鍵字與搜尋意圖、 內容差距、基礎網站架構、content brief、四篇 SEO 寫作實作、流量或排名問題教學， 以及 robots.txt、sitemap、title、canonical、Core Web Vitals 等概念與操作問題。 Do not use for a one-shot full-site audit report or health score, ghostwritten content delivery, PBN/site building, or paid-ad-only advice.
axolotl
davila7
Expert guidance for fine-tuning LLMs with Axolotl - YAML configs, 100+ models, LoRA/QLoRA, DPO/KTO/ORPO/GRPO, multimodal support