API Dev
API design, REST, GraphQL
dbsnp-database
by jaechang-hits
"Query NCBI dbSNP for SNP records by rsID, gene, or genomic region via E-utilities (esearch, efetch, epost) and NCBI Variation Services REST API. Retrieve allele data, minor allele frequency, variant class (SNV, indel, MNV), clinical significance links, and cross-database IDs (ClinVar, dbVar, 1000G). Free access; 3 req/sec without API key, 10 req/sec with key. For clinical pathogenicity classifications use clinvar-database; for population frequencies use gnomad-database."
cosmic-database
by jaechang-hits
"Query COSMIC (Catalogue Of Somatic Mutations In Cancer) for cancer somatic mutations, gene census data, mutational signatures, drug resistance variants, and cancer gene annotations. REST API v3.1 supports gene/sample/variant queries. Free registration required. For germline clinical variants use clinvar-database; for drug-target data use opentargets-database or chembl-database-bioactivity."
ena-database
by jaechang-hits
"European Nucleotide Archive (ENA) REST API access for genomic sequences, raw reads, assemblies, and annotations. Portal API search with query syntax, Browser API retrieval (XML/FASTA/EMBL), file reports for FASTQ/BAM download URLs, taxonomy queries, cross-references. For multi-database Python queries prefer bioservices; for NCBI-specific queries use pubmed-database or Biopython Entrez."
ensembl-database
by jaechang-hits
"Query Ensembl REST API for gene/transcript/variant annotations across 300+ species. Retrieve gene info by symbol/ID, sequence, cross-references (HGNC, RefSeq, UniProt), variants, regulatory features, comparative genomics. For bulk local access use pyensembl; for pathway lookups use kegg-database or reactome-database."
clinpgx-database
by jaechang-hits
"Query PharmGKB (Clinical Pharmacogenomics) database via REST API for drug-gene interactions, clinical annotations, dosing guidelines (CPIC, DPWG), variant-drug associations, and pharmacogenomic pathways. Search by gene, drug, rsID, or pathway. No authentication required. For somatic cancer pharmacogenomics use cosmic-database or opentargets-database; for drug structures use chembl-database-bioactivity."
bioservices-multi-database
by jaechang-hits
Unified Python interface to 40+ bioinformatics web services via bioservices library. Query UniProt proteins, KEGG pathways, ChEMBL/ChEBI/PubChem compounds, run BLAST searches, map identifiers across databases, retrieve GO annotations, and find protein-protein interactions. For single-database deep queries use dedicated tools (gget for Ensembl, pubchempy for PubChem); bioservices excels at cross-database integration workflows.
aiox-architect
by SynkraAI
Architect (Aria). Use for system architecture (fullstack, backend, frontend, infrastructure), technology stack selection (technical evaluation), API design (REST/GraphQL/tRPC/We...
ai-shifu Skills Entry
by ai-shifu
Troubleshooting knowledge that needs step-by-step execution or long-term reuse belongs in the relevant subproject SKILL.md system.
minimax
by vm0-ai
MiniMax API via curl. Use this skill for Chinese LLM chat, text-to-speech, and AI video generation.
node-red
by tonylofgren
Use when user mentions "node-red" anywhere in their request (including compound words like "node-redflöde", "node-red-flow"). The term "Node-RED" is a product name that appears unchanged in all languages. NOT for: YAML automations (use home-assistant skill), device firmware (use esphome skill).
debug
by whawkinsiv
"Use this skill when features break, users report errors, deployments fail, or tests don't pass. Guides systematic debugging: reproducing bugs, gathering diagnostic info, reading error messages, and working with AI tools to fix issues efficiently."
testing-integration
by yonatangross
Integration and contract testing patterns — API endpoint tests, component integration, database testing, Pact contract verification, property-based testing, and Zod schema validation. Use when testing API boundaries, verifying contracts, or validating cross-service integration.
api-design
by yonatangross
API contract design for REST and GraphQL, covering resource shape, URL and header versioning with deprecation windows, RFC 9457 Problem Details error handling, and OpenAPI specs. Use when specifying the wire contract an endpoint exposes, choosing a versioning scheme, or standardizing error response bodies across services. Framework-agnostic protocol layer, not runtime implementation.
api-design
by yonatangross
API design patterns for REST/GraphQL framework design, versioning strategies, and RFC 9457 error handling. Use when designing API endpoints, choosing versioning schemes, implementing Problem Details errors, or building OpenAPI specifications.
langgraph
by yonatangross
LangGraph workflow patterns for state management, routing, parallel execution, supervisor-worker, tool calling, checkpointing, human-in-loop, streaming, subgraphs, and functional API. Use when building LangGraph pipelines, multi-agent systems, or AI workflows.
python-backend
by yonatangross
Python backend patterns for asyncio, FastAPI, SQLAlchemy 2.0 async, and connection pooling. Use when building async Python services, FastAPI endpoints, database sessions, or connection pool tuning.
github-operations
by yonatangross
GitHub CLI operations for issues, PRs, milestones, and Projects v2. Covers gh commands, REST API patterns, and automation scripts. Use when managing GitHub issues, PRs, milestones, or Projects with gh.
Technical Documentation
by takeokunn
This skill should be used when the user asks to "write documentation", "create README", "API docs", "design document", "specification", "user guide", or needs documentation guidance. Provides comprehensive documentation patterns for developers, teams, and end-users in both English and Japanese.
functions
by browserbase
Guide Claude through deploying serverless browser automation using the official bb CLI
configuring
by oaustegard
Universal environment variable loader for AI agent environments. Loads secrets and config from Claude.ai, Claude Code, OpenAI Codex, Jules, and standard .env files.
invoking-gemini
by oaustegard
Invokes Google Gemini models for structured outputs, multi-modal tasks, and Google-specific features. Use when users request Gemini, structured JSON output, Google API integration, or cost-effective parallel processing.
orchestrating-agents
by oaustegard
Orchestrates parallel API instances, delegated sub-tasks, and multi-agent workflows with streaming and tool-enabled delegation patterns. Use for parallel analysis, multi-perspective reviews, or complex task decomposition.
building-github-index
by oaustegard
Generate progressive disclosure indexes for GitHub repositories to use as Claude project knowledge. Use when setting up projects referencing external documentation, creating searchable indexes of technical blogs or knowledge bases, combining multiple repos into one index, or when user mentions "index", "github repo", "project knowledge", or "documentation reference".
accessing-github-repos
by oaustegard
GitHub repository access in containerized environments using REST API and credential detection. Use when git clone fails, or when accessing private repos/writing files via API.