Processing
Data transformation and parsing
shadcn-ui
by jezweb
"Install and configure shadcn/ui components for React projects. Guides component selection, installation order, dependency management, customisation with semantic tokens, and common UI recipes (forms, data tables, navigation, modals). Use after tailwind-theme-builder has set up the theme infrastructure, when adding components, building forms, creating data tables, or setting up navigation."
3d-cv-labeling-2026
by curiositech
Expert in 3D computer vision labeling tools, workflows, and AI-assisted annotation for LiDAR, point clouds, and sensor fusion. Covers SAM4D/Point-SAM, human-in-the-loop architectures, and vertical-specific training strategies. Activate on '3D labeling', 'point cloud annotation', 'LiDAR labeling', 'SAM 3D', 'SAM4D', 'sensor fusion annotation', '3D bounding box', 'semantic segmentation point cloud'. NOT for 2D image labeling (use clip-aware-embeddings), general ML training (use ml-engineer), video annotation without 3D (use computer-vision-pipeline), or VLM prompt engineering (use prompt-engineer).
geo-database
by jaechang-hits
"Query NCBI Gene Expression Omnibus (GEO) for gene expression datasets and sample metadata via GEOparse Python library and E-utilities. Search datasets by keyword/organism/platform, download GSE series matrices, parse GPL platform annotations, extract GSM sample metadata, and load expression matrices into pandas. For single-cell data use cellxgene-census; for programmatic multi-DB access use gget-genomic-databases."
omero-integration
by jaechang-hits
"OMERO is an open-source platform for biological image data management. Use the omero-py Python client to connect to an OMERO server, search and retrieve images as numpy arrays, annotate images with tags and key-value pairs, manage ROIs, and integrate OMERO image data into downstream analysis pipelines — all programmatically without the OMERO desktop GUI."
pymc-bayesian-modeling
by jaechang-hits
"Bayesian modeling with PyMC 5. 8-step workflow: define model, set priors, define likelihood, sample (NUTS/ADVI), diagnose (R-hat, ESS, divergences), interpret posteriors, compare models (LOO/WAIC), predict. Hierarchical, logistic, GP model variants. Prior/posterior predictive checks."
bcftools-variant-manipulation
by jaechang-hits
"Command-line toolkit for VCF/BCF variant file manipulation. Filter, merge, annotate, query, normalize, and compute statistics on variant call files. Essential for post-variant-calling pipelines: quality filtering, multi-sample merging, rsID annotation, and genotype extraction. Companion to samtools in the HTSlib ecosystem. Use GATK instead for complex indel realignment during variant calling; use VCFtools instead for population genetics statistics."
archs4-database
by jaechang-hits
"Query uniformly processed RNA-seq gene expression profiles, tissue-specific expression patterns, and co-expression networks from the ARCHS4 database REST API. Retrieve z-score normalized expression across 1M+ human and mouse samples, find co-expressed genes, search samples by metadata, and download HDF5 expression matrices. For variant-level population genetics use gnomad-database; for pathway enrichment from gene lists use gget-genomic-databases (Enrichr)."
clinical-decision-support-documents
by jaechang-hits
"Guidelines for generating clinical decision support (CDS) documents: patient cohort analyses (biomarker-stratified outcomes) and treatment recommendation reports (GRADE-graded evidence). Covers document structure, executive summary design, evidence grading (GRADE 1A–2C), statistical reporting (HR, CI, survival), and biomarker integration. Use when creating pharmaceutical research documents, clinical guidelines, or regulatory submissions."
encode-database
by jaechang-hits
"Query the ENCODE Portal REST API for regulatory genomics data: TF ChIP-seq experiments, ATAC-seq/DNase-seq accessibility peaks, histone mark tracks, and RNA-seq datasets across 1000+ cell types and tissues. Search experiments by assay, biosample, or target protein; download BED/bigWig files; retrieve candidate cis-regulatory elements (cCREs) from ENCODE SCREEN by genomic region or gene. Use for finding regulatory tracks to annotate variants, identifying open chromatin in a cell type of interest, and downloading peak files for ChIP-seq or ATAC-seq analysis. For regulatory variant scoring use regulomedb-database; for GWAS associations use gwas-database."
gnomad-database
by jaechang-hits
"Query gnomAD v4 population variant frequencies via GraphQL API. Retrieve allele counts and frequencies stratified by ancestry group (AFR, AMR, EAS, NFE, SAS, FIN, ASJ, MID), gene-level constraint metrics (pLI, LOEUF, missense z-score), and read depth coverage. Identify variants with low population frequency or under evolutionary constraint. For clinical pathogenicity classifications use clinvar-database; for GWAS associations use gwas-database."
pyimagej-fiji-bridge
by jaechang-hits
"Python bridge to ImageJ2/Fiji enabling macro execution, plugin calls (Bio-Formats, TrackMate, Analyze Particles), bidirectional NumPy↔ImagePlus/ImgLib2 data exchange, and ImageJ Ops from Python. Use for automating Fiji-specific workflows headlessly from Python scripts. Use scikit-image instead for pure Python pipelines that do not require Fiji plugins; use napari for interactive visualization."
dbsnp-database
by jaechang-hits
"Query NCBI dbSNP for SNP records by rsID, gene, or genomic region via E-utilities (esearch, efetch, epost) and NCBI Variation Services REST API. Retrieve allele data, minor allele frequency, variant class (SNV, indel, MNV), clinical significance links, and cross-database IDs (ClinVar, dbVar, 1000G). Free access; 3 req/sec without API key, 10 req/sec with key. For clinical pathogenicity classifications use clinvar-database; for population frequencies use gnomad-database."
clinpgx-database
by jaechang-hits
"Query PharmGKB (Clinical Pharmacogenomics) database via REST API for drug-gene interactions, clinical annotations, dosing guidelines (CPIC, DPWG), variant-drug associations, and pharmacogenomic pathways. Search by gene, drug, rsID, or pathway. No authentication required. For somatic cancer pharmacogenomics use cosmic-database or opentargets-database; for drug structures use chembl-database-bioactivity."
cosmic-database
by jaechang-hits
"Query COSMIC (Catalogue Of Somatic Mutations In Cancer) for cancer somatic mutations, gene census data, mutational signatures, drug resistance variants, and cancer gene annotations. REST API v3.1 supports gene/sample/variant queries. Free registration required. For germline clinical variants use clinvar-database; for drug-target data use opentargets-database or chembl-database-bioactivity."
napari-image-viewer
by jaechang-hits
"Interactive multi-dimensional image viewer for scientific microscopy data. Napari displays 2D/3D/4D arrays as Image, Labels, Points, Shapes, and Tracks layers; supports real-time annotation, plugin-based analysis, and headless screenshot export. Core visualization tool for bioimage analysis workflows. Use ImageJ/FIJI for macro-based processing; use napari for Python-native interactive visualization and plugin-based deep learning segmentation review."
ena-database
by jaechang-hits
"European Nucleotide Archive (ENA) REST API access for genomic sequences, raw reads, assemblies, and annotations. Portal API search with query syntax, Browser API retrieval (XML/FASTA/EMBL), file reports for FASTQ/BAM download URLs, taxonomy queries, cross-references. For multi-database Python queries prefer bioservices; for NCBI-specific queries use pubmed-database or Biopython Entrez."
cellxgene-census
by jaechang-hits
"Query CELLxGENE Census (61M+ cells) programmatically. Search by cell type, tissue, disease, organism. Get expression matrices as AnnData, stream large queries out-of-core, train PyTorch models on single-cell data. For analyzing your own data use scanpy; for annotated data manipulation use anndata."
ensembl-database
by jaechang-hits
"Query Ensembl REST API for gene/transcript/variant annotations across 300+ species. Retrieve gene info by symbol/ID, sequence, cross-references (HGNC, RefSeq, UniProt), variants, regulatory features, comparative genomics. For bulk local access use pyensembl; for pathway lookups use kegg-database or reactome-database."
simpleitk-image-registration
by jaechang-hits
"Register, segment, filter, and resample 3D medical images (MRI, CT, microscopy) using SimpleITK's Python API with support for DICOM, NIfTI, and multi-modal image analysis. Provides rigid/affine/deformable registration, threshold and region-growing segmentation, Gaussian and morphological filtering, label statistics, and format conversion. Use when aligning volumetric images across timepoints or modalities, automating segmentation of fluorescence microscopy, or converting DICOM series to NIfTI for analysis pipelines."
imaging-data-commons
by jaechang-hits
"Query NCI Imaging Data Commons (IDC) for cancer radiology and pathology imaging datasets hosted on Google Cloud. Search DICOM collections by modality, anatomical site, cancer type, or collection name. Download images via Google Cloud Storage or IDAT tool. 50TB+ of publicly accessible DICOM images. Requires Google Cloud account for large downloads; small queries work without billing. For local DICOM processing use pydicom-medical-imaging; for whole-slide pathology use histolab."
cbioportal-database
by jaechang-hits
"Access TCGA and other cancer genomics datasets via cBioPortal REST API. Retrieve somatic mutations, copy number alterations, gene expression profiles, and clinical data (survival, stage, treatment) for thousands of cancer studies. Use for tumor mutation burden analysis, oncoprint queries, and survival analysis. For population variant frequencies use gnomad-database; for drug-gene interactions use dgidb-database."
onvifscan
by BrownFineSecurity
ONVIF device security scanner for testing authentication and brute-forcing credentials. Use when you need to assess security of IP cameras or ONVIF-enabled devices.
netflows
by BrownFineSecurity
Network flow extractor that analyzes pcap/pcapng files to identify outbound connections with automatic DNS hostname resolution. Use when you need to enumerate network destinations, identify what hosts a device communicates with, or map IP addresses to hostnames from packet captures.
Chipsec - UEFI Firmware Static Analysis
by BrownFineSecurity
IoT HackBot: A collection of Claude Skills and custom tooling for hybrid IoT pentesting